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Crohn's disease commonly affects the small and large intestines. Its symptoms include ulcers and intestinal stenosis, and its diagnosis is currently performed using an endoscope. However, because the endoscope cannot pass through the stenosed parts of the intestines, diagnosis of the entire intestines is difficult. A CT image-based method is expected to become an alternative way for the diagnosis of Crohn's disease because it enables observation of the entire intestine even if stenosis exists. To achieve efficient CT image-based diagnosis, diagnostic-aid by computers is required. This paper presents an automated detection method of the surface of ulcers in the small and large intestines from fecal tagging CT images. Ulcers cause rough surfaces on the intestinal wall and consist of small convex and concave (CC) regions. We detect them by blob and inverse-blob structure enhancement filters. A roughness value is utilized to reduce the false positives of the detection results. Many CC regions are concentrated in ulcers. The roughness value evaluates the concentration ratio of the detected regions. Detected regions with low roughness values are removed by a thresholding process. The thickness of the intestinal lumen and the CT values of the surrounding tissue of the intestinal lumen are also used to reduce false positives. Experimental results using ten cases of CT images showed that our proposed method detects 70.6% of ulcers with 12.7 FPs/case. The proposed method detected most of the ulcers.
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Masahiro ODA, Takayuki KITASAKA, Kazuhiro FURUKAWA, Osamu WATANABE, Takafumi ANDO, Hidemi GOTO, Kensaku MORI, "Automated Ulcer Detection Method from CT Images for Computer Aided Diagnosis of Crohn's Disease" in IEICE TRANSACTIONS on Information,
vol. E96-D, no. 4, pp. 808-818, April 2013, doi: 10.1587/transinf.E96.D.808.
Abstract: Crohn's disease commonly affects the small and large intestines. Its symptoms include ulcers and intestinal stenosis, and its diagnosis is currently performed using an endoscope. However, because the endoscope cannot pass through the stenosed parts of the intestines, diagnosis of the entire intestines is difficult. A CT image-based method is expected to become an alternative way for the diagnosis of Crohn's disease because it enables observation of the entire intestine even if stenosis exists. To achieve efficient CT image-based diagnosis, diagnostic-aid by computers is required. This paper presents an automated detection method of the surface of ulcers in the small and large intestines from fecal tagging CT images. Ulcers cause rough surfaces on the intestinal wall and consist of small convex and concave (CC) regions. We detect them by blob and inverse-blob structure enhancement filters. A roughness value is utilized to reduce the false positives of the detection results. Many CC regions are concentrated in ulcers. The roughness value evaluates the concentration ratio of the detected regions. Detected regions with low roughness values are removed by a thresholding process. The thickness of the intestinal lumen and the CT values of the surrounding tissue of the intestinal lumen are also used to reduce false positives. Experimental results using ten cases of CT images showed that our proposed method detects 70.6% of ulcers with 12.7 FPs/case. The proposed method detected most of the ulcers.
URL: https://global.ieice.org/en_transactions/information/10.1587/transinf.E96.D.808/_p
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@ARTICLE{e96-d_4_808,
author={Masahiro ODA, Takayuki KITASAKA, Kazuhiro FURUKAWA, Osamu WATANABE, Takafumi ANDO, Hidemi GOTO, Kensaku MORI, },
journal={IEICE TRANSACTIONS on Information},
title={Automated Ulcer Detection Method from CT Images for Computer Aided Diagnosis of Crohn's Disease},
year={2013},
volume={E96-D},
number={4},
pages={808-818},
abstract={Crohn's disease commonly affects the small and large intestines. Its symptoms include ulcers and intestinal stenosis, and its diagnosis is currently performed using an endoscope. However, because the endoscope cannot pass through the stenosed parts of the intestines, diagnosis of the entire intestines is difficult. A CT image-based method is expected to become an alternative way for the diagnosis of Crohn's disease because it enables observation of the entire intestine even if stenosis exists. To achieve efficient CT image-based diagnosis, diagnostic-aid by computers is required. This paper presents an automated detection method of the surface of ulcers in the small and large intestines from fecal tagging CT images. Ulcers cause rough surfaces on the intestinal wall and consist of small convex and concave (CC) regions. We detect them by blob and inverse-blob structure enhancement filters. A roughness value is utilized to reduce the false positives of the detection results. Many CC regions are concentrated in ulcers. The roughness value evaluates the concentration ratio of the detected regions. Detected regions with low roughness values are removed by a thresholding process. The thickness of the intestinal lumen and the CT values of the surrounding tissue of the intestinal lumen are also used to reduce false positives. Experimental results using ten cases of CT images showed that our proposed method detects 70.6% of ulcers with 12.7 FPs/case. The proposed method detected most of the ulcers.},
keywords={},
doi={10.1587/transinf.E96.D.808},
ISSN={1745-1361},
month={April},}
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TY - JOUR
TI - Automated Ulcer Detection Method from CT Images for Computer Aided Diagnosis of Crohn's Disease
T2 - IEICE TRANSACTIONS on Information
SP - 808
EP - 818
AU - Masahiro ODA
AU - Takayuki KITASAKA
AU - Kazuhiro FURUKAWA
AU - Osamu WATANABE
AU - Takafumi ANDO
AU - Hidemi GOTO
AU - Kensaku MORI
PY - 2013
DO - 10.1587/transinf.E96.D.808
JO - IEICE TRANSACTIONS on Information
SN - 1745-1361
VL - E96-D
IS - 4
JA - IEICE TRANSACTIONS on Information
Y1 - April 2013
AB - Crohn's disease commonly affects the small and large intestines. Its symptoms include ulcers and intestinal stenosis, and its diagnosis is currently performed using an endoscope. However, because the endoscope cannot pass through the stenosed parts of the intestines, diagnosis of the entire intestines is difficult. A CT image-based method is expected to become an alternative way for the diagnosis of Crohn's disease because it enables observation of the entire intestine even if stenosis exists. To achieve efficient CT image-based diagnosis, diagnostic-aid by computers is required. This paper presents an automated detection method of the surface of ulcers in the small and large intestines from fecal tagging CT images. Ulcers cause rough surfaces on the intestinal wall and consist of small convex and concave (CC) regions. We detect them by blob and inverse-blob structure enhancement filters. A roughness value is utilized to reduce the false positives of the detection results. Many CC regions are concentrated in ulcers. The roughness value evaluates the concentration ratio of the detected regions. Detected regions with low roughness values are removed by a thresholding process. The thickness of the intestinal lumen and the CT values of the surrounding tissue of the intestinal lumen are also used to reduce false positives. Experimental results using ten cases of CT images showed that our proposed method detects 70.6% of ulcers with 12.7 FPs/case. The proposed method detected most of the ulcers.
ER -