The simulation of a specific absorption rate (SAR) with a temperature distribution becomes more important in the treatment planning for microwave hyperthermia. The simulation technique can also be used to estimate SAR distribution inside human body under hazardous electromagnetic (EM) field circumstances. In the simulation, to use exact permittivity of biological tissues becomes very important to obtain accurate SAR distribution. The permittivity of the medium is very sensitive to the temperature. Therefore, it is considered that the SAR distribution is also very sensitive to the tissue temperature. In this paper, SAR distribution is calculated using FDTD method considering tissue temperature under the electromagnetic (EM) field irradiation. Simulations of temperature distribution are also performed using heat transfer equation. In addition, temperature depending blood flow is taking into account to obtain temperature depending SAR distribution. The results can be used to estimate temperature depending heat generation which can be applied such as microwave hyperthermia treatment.

A partially ferrites and dielectric loaded water filled waveguide applicator is presented which can be used for microwave heating of tissues. The applicator can change its heating pattern by changing the external DC magnetic field applied to the ferrites. The electromagnetic (EM) field distribution inside the applicator is obtained theoretically and the simulated EM field inside the applicator is checked experimentally using 430MHz. Furthermore, on the basis of the EM field distribution inside the applicator, simulations of SAR distribution inside lossy homogeneous human tissue as muscle are performed using finite difference time domain (FD-TD) method. Simulated data of Specific Absorption Rate (SAR) distribution is compared with the experimental ones. Simulations of temperature distribution are also performed using heat transfer equation. Simulated data of temperature elevation distribution is compared with the experimental ones. The simulated results agree well with the experimental ones and it is confirmed that the heating pattern can be changed by external DC magnetic field applied to the applicator. The results obtained here show that the partially ferrites and dielectric loaded water filled waveguide applicator which operates at 430 MHz can change its heating pattern without changing its setup and can heat local target on the human body for hyperthermia treatment.

In the early stage of hyperthermia, a large number of engineering efforts have been done in the development or the improvement of the heating and temperature measuring techniques. However, they were not always satisfactory clinically. Thus, even in this moment, various engineering researches as well as the electromagnetic techniques for hyperthermia should be build up rapidly. This paper describes some of the highlights of developed or ongoing electromagnetic heating techniques in hyperthermia and identities a trend of emerging electromagnetic heating. Furthermore, the author emphasizes that few medical engineering efforts have been done in the boundary field between pure physics and clinics, and the proper way to develop the hyperthermia equipment is the best use of successes in the three essential regions: Physics, Biology and Clinics.

A light, thin and flexible applicator using a microstrip patch array for microwave heating is presented and tested in this work. The applicator is made of a flat silicone rubber bag, inside of which flows cooling water. EM coupling feeding is applied, which has no direct contact between the feed and the patch, to improve durability and reliability when it is repeatedly applied to the uneven surface of the heated portion of the human body. Simulations of SAR distribution are performed using the finite difference time domain (FD-TD) method. Simulated data are compared with the experimental ones using cubic and cylindrical phantom models with single and multielement patch applicators. Simulations of temperature distribution are also performed using the heat transfer equation. Simulated data are compared with the experimental ones using cubic and cylindrical phantom models. The simulated results agree well with the experimental ones. The results obtained here show that the multielement flexible microstrip patch applicator which operates at 430MHz can heat a relatively shallow and widespread area on the human body for hyperthermia treatments.

A dielectric rod waveguide applicator for microwave heating such as microwave hyperthermia is described. The applicator consists of the acrylic cylinder filled with deionized water. By circulating the deionized water, the dielectric rod waveguide applicator acts as a surface cooling device, so that it doesn't need any bolus. This surface cooling device enables the dielectric rod waveguide applicator to control the site of effective heating region along the depth axis. Useful pattern of the circular or spheroidal shape and axially symmetric effective heating region were obtained. Furthermore metal strips provided on the aperture of applicator control the shape of the heating pattern.

A new model for a computer simulation of RF capacitive type hyperthermia has been developed by taking account of the following points. Blood flow is usually determined by many physiological parameters, but is regarded as a function of only blood temperature under some conditions. The temperature dependence of blood flow of tumors and normal tissues is assumed by referring the data obtained by Song et al. and Tanaka. The blood temperature which is elevated by externally applied power significantly affects temperatures of the body and the tumors. The transport of heat from the body surface is studied by considering air convection. These points are examined by experiments on a computer with simple phantom models and real patients. The results of simulation on the patient have shown a good agreement with clinical inspection based on CT images and a temperature of the stomach.