An all-digital clock deskew buffer with variable duty cycles is presented. The proposed circuit aligns the input and output clocks with two cycles. A pulsewidth detector using the sequential time-to-digital conversion is employed to detect the duty cycle. The output clock with adjustable duty cycles can be generated. The proposed circuit has been fabricated in a 0.35 µm CMOS technology. The measured duty cycle of the output clock can be adjusted from 30% to 70% in steps of 10%. The operation frequency range is from 400 MHz to 600 MHz.