Functional Mapping of Optically Detected Neural Activity onto a Standardized Cortical Structure of Rodent Barrels

Ichiro TAKASHIMA; Riichi KAJIWARA; Toshio IIJIMA

Functional Mapping of Optically Detected Neural Activity onto a Standardized Cortical Structure of Rodent Barrels

Ichiro TAKASHIMA, Riichi KAJIWARA, Toshio IIJIMA

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The concept of a "standardized brain" is familiar in modern functional neuro-imaging techniques including PET and fMRI, but it has never been adopted for optical imaging studies that deal with a regional cortical area rather than the whole brain. In this paper, we propose a "standardized barrel cortex" for rodents, and present a method for mapping optically detected neural activity onto the standard cortex. The standard cortex is defined as a set of simple cortical columns, which are modeled on the cytoarchitectonic patterns of cell aggregates in cortical layer IV of the barrel cortex. Referring to its underlying anatomical structure, the method warps the surface image of individual cortices to fit the standard cortex. The cortex is warped using a two-dimensional free-form deformation technique with direct manipulation. Since optical imaging provides a map of neural activity on the cortical surface, the warping consequently remaps it on the standard cortex. Data presented in this paper show that somatosensory evoked neural activity is successfully represented on the standardized cortex, suggesting that the combination of optical imaging with our method is a promising approach for investigating the functional architecture of the cortex.

Publication: IEICE TRANSACTIONS on Information Vol.E85-D No.1 pp.143-151

Publication Date: 2002/01/01

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Type of Manuscript: Special Section PAPER (Special Issue on Measurements and Visualization Technology of Biological Information)

Category: Optical Imaging

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Ichiro TAKASHIMA, Riichi KAJIWARA, Toshio IIJIMA, "Functional Mapping of Optically Detected Neural Activity onto a Standardized Cortical Structure of Rodent Barrels" in IEICE TRANSACTIONS on Information, vol. E85-D, no. 1, pp. 143-151, January 2002, doi: .
Abstract: The concept of a "standardized brain" is familiar in modern functional neuro-imaging techniques including PET and fMRI, but it has never been adopted for optical imaging studies that deal with a regional cortical area rather than the whole brain. In this paper, we propose a "standardized barrel cortex" for rodents, and present a method for mapping optically detected neural activity onto the standard cortex. The standard cortex is defined as a set of simple cortical columns, which are modeled on the cytoarchitectonic patterns of cell aggregates in cortical layer IV of the barrel cortex. Referring to its underlying anatomical structure, the method warps the surface image of individual cortices to fit the standard cortex. The cortex is warped using a two-dimensional free-form deformation technique with direct manipulation. Since optical imaging provides a map of neural activity on the cortical surface, the warping consequently remaps it on the standard cortex. Data presented in this paper show that somatosensory evoked neural activity is successfully represented on the standardized cortex, suggesting that the combination of optical imaging with our method is a promising approach for investigating the functional architecture of the cortex.
URL: https://global.ieice.org/en_transactions/information/10.1587/e85-d_1_143/_p

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@ARTICLE{e85-d_1_143,
author={Ichiro TAKASHIMA, Riichi KAJIWARA, Toshio IIJIMA, },
journal={IEICE TRANSACTIONS on Information},
title={Functional Mapping of Optically Detected Neural Activity onto a Standardized Cortical Structure of Rodent Barrels},
year={2002},
volume={E85-D},
number={1},
pages={143-151},
abstract={The concept of a "standardized brain" is familiar in modern functional neuro-imaging techniques including PET and fMRI, but it has never been adopted for optical imaging studies that deal with a regional cortical area rather than the whole brain. In this paper, we propose a "standardized barrel cortex" for rodents, and present a method for mapping optically detected neural activity onto the standard cortex. The standard cortex is defined as a set of simple cortical columns, which are modeled on the cytoarchitectonic patterns of cell aggregates in cortical layer IV of the barrel cortex. Referring to its underlying anatomical structure, the method warps the surface image of individual cortices to fit the standard cortex. The cortex is warped using a two-dimensional free-form deformation technique with direct manipulation. Since optical imaging provides a map of neural activity on the cortical surface, the warping consequently remaps it on the standard cortex. Data presented in this paper show that somatosensory evoked neural activity is successfully represented on the standardized cortex, suggesting that the combination of optical imaging with our method is a promising approach for investigating the functional architecture of the cortex.},
keywords={},
doi={},
ISSN={},
month={January},}

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TY - JOUR
TI - Functional Mapping of Optically Detected Neural Activity onto a Standardized Cortical Structure of Rodent Barrels
T2 - IEICE TRANSACTIONS on Information
SP - 143
EP - 151
AU - Ichiro TAKASHIMA
AU - Riichi KAJIWARA
AU - Toshio IIJIMA
PY - 2002
DO -
JO - IEICE TRANSACTIONS on Information
SN -
VL - E85-D
IS - 1
JA - IEICE TRANSACTIONS on Information
Y1 - January 2002
AB - The concept of a "standardized brain" is familiar in modern functional neuro-imaging techniques including PET and fMRI, but it has never been adopted for optical imaging studies that deal with a regional cortical area rather than the whole brain. In this paper, we propose a "standardized barrel cortex" for rodents, and present a method for mapping optically detected neural activity onto the standard cortex. The standard cortex is defined as a set of simple cortical columns, which are modeled on the cytoarchitectonic patterns of cell aggregates in cortical layer IV of the barrel cortex. Referring to its underlying anatomical structure, the method warps the surface image of individual cortices to fit the standard cortex. The cortex is warped using a two-dimensional free-form deformation technique with direct manipulation. Since optical imaging provides a map of neural activity on the cortical surface, the warping consequently remaps it on the standard cortex. Data presented in this paper show that somatosensory evoked neural activity is successfully represented on the standardized cortex, suggesting that the combination of optical imaging with our method is a promising approach for investigating the functional architecture of the cortex.
ER -