A Multi-Channel Electrochemical Measurement System for Biomolecular Detection

Wei-Chiun LIU; Bin-Da LIU; Chia-Ling WEI

doi:10.1587/transele.E99.C.1295

A Multi-Channel Electrochemical Measurement System for Biomolecular Detection

Wei-Chiun LIU, Bin-Da LIU, Chia-Ling WEI

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A modularized, low-cost, and non-invasive electrochemical examination platform is proposed in this work. Melatonin has been found to be a possible significant indicator molecule in the detection of breast cancer. 3-hydroxyanthranilic acid and nuclear matrix protein 22 can be used as a significant index for potential bladder cancer risks. The proposed system was verified by measuring the melatonin, 3-hydroxyanthranilic acid and nuclear matrix protein 22. Cyclic voltammetry and molecularly imprinted polymers were used in the experiments. Screen-printed electrodes were coated with a film imprinted with target molecules. The measurement results of the proposed system were compared with those of a commercial potentiostat. The two sets of results were very similar. Moreover, the proposed system can be expanded to a four-channel system, which can perform four measurements simultaneously. The proposed system also provides convenient graphical user interface for real-time monitoring and records the information of the redox reactions.

Publication: IEICE TRANSACTIONS on Electronics Vol.E99-C No.11 pp.1295-1303

Publication Date: 2016/11/01

Publicized

Online ISSN: 1745-1353

DOI: 10.1587/transele.E99.C.1295

Type of Manuscript: PAPER

Category: Electronic Circuits

Authors

Wei-Chiun LIU
  National Cheng Kung University
Bin-Da LIU
  National Cheng Kung University
Chia-Ling WEI
  National Cheng Kung University

Keyword

3-hydroxyanthranilic acid, electrochemical, melatonin, molecularly imprinted polymers, nuclear matrix protein 22

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Wei-Chiun LIU, Bin-Da LIU, Chia-Ling WEI, "A Multi-Channel Electrochemical Measurement System for Biomolecular Detection" in IEICE TRANSACTIONS on Electronics, vol. E99-C, no. 11, pp. 1295-1303, November 2016, doi: 10.1587/transele.E99.C.1295.
Abstract: A modularized, low-cost, and non-invasive electrochemical examination platform is proposed in this work. Melatonin has been found to be a possible significant indicator molecule in the detection of breast cancer. 3-hydroxyanthranilic acid and nuclear matrix protein 22 can be used as a significant index for potential bladder cancer risks. The proposed system was verified by measuring the melatonin, 3-hydroxyanthranilic acid and nuclear matrix protein 22. Cyclic voltammetry and molecularly imprinted polymers were used in the experiments. Screen-printed electrodes were coated with a film imprinted with target molecules. The measurement results of the proposed system were compared with those of a commercial potentiostat. The two sets of results were very similar. Moreover, the proposed system can be expanded to a four-channel system, which can perform four measurements simultaneously. The proposed system also provides convenient graphical user interface for real-time monitoring and records the information of the redox reactions.
URL: https://global.ieice.org/en_transactions/electronics/10.1587/transele.E99.C.1295/_p

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@ARTICLE{e99-c_11_1295,
author={Wei-Chiun LIU, Bin-Da LIU, Chia-Ling WEI, },
journal={IEICE TRANSACTIONS on Electronics},
title={A Multi-Channel Electrochemical Measurement System for Biomolecular Detection},
year={2016},
volume={E99-C},
number={11},
pages={1295-1303},
abstract={A modularized, low-cost, and non-invasive electrochemical examination platform is proposed in this work. Melatonin has been found to be a possible significant indicator molecule in the detection of breast cancer. 3-hydroxyanthranilic acid and nuclear matrix protein 22 can be used as a significant index for potential bladder cancer risks. The proposed system was verified by measuring the melatonin, 3-hydroxyanthranilic acid and nuclear matrix protein 22. Cyclic voltammetry and molecularly imprinted polymers were used in the experiments. Screen-printed electrodes were coated with a film imprinted with target molecules. The measurement results of the proposed system were compared with those of a commercial potentiostat. The two sets of results were very similar. Moreover, the proposed system can be expanded to a four-channel system, which can perform four measurements simultaneously. The proposed system also provides convenient graphical user interface for real-time monitoring and records the information of the redox reactions.},
keywords={},
doi={10.1587/transele.E99.C.1295},
ISSN={1745-1353},
month={November},}

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TY - JOUR
TI - A Multi-Channel Electrochemical Measurement System for Biomolecular Detection
T2 - IEICE TRANSACTIONS on Electronics
SP - 1295
EP - 1303
AU - Wei-Chiun LIU
AU - Bin-Da LIU
AU - Chia-Ling WEI
PY - 2016
DO - 10.1587/transele.E99.C.1295
JO - IEICE TRANSACTIONS on Electronics
SN - 1745-1353
VL - E99-C
IS - 11
JA - IEICE TRANSACTIONS on Electronics
Y1 - November 2016
AB - A modularized, low-cost, and non-invasive electrochemical examination platform is proposed in this work. Melatonin has been found to be a possible significant indicator molecule in the detection of breast cancer. 3-hydroxyanthranilic acid and nuclear matrix protein 22 can be used as a significant index for potential bladder cancer risks. The proposed system was verified by measuring the melatonin, 3-hydroxyanthranilic acid and nuclear matrix protein 22. Cyclic voltammetry and molecularly imprinted polymers were used in the experiments. Screen-printed electrodes were coated with a film imprinted with target molecules. The measurement results of the proposed system were compared with those of a commercial potentiostat. The two sets of results were very similar. Moreover, the proposed system can be expanded to a four-channel system, which can perform four measurements simultaneously. The proposed system also provides convenient graphical user interface for real-time monitoring and records the information of the redox reactions.
ER -