In many real application scenarios of image segmentation problems involving limited and low-quality data, employing prior information can significantly improve the segmentation result. For example, the shape of the object is a kind of common prior information. In this paper, we introduced a new kind of prior information, which is named by prior distribution. On the basis of nonparametric statistical active contour model, we proposed a novel distribution prior model. Unlike traditional shape prior model, our model is not sensitive to the shapes of object boundary. Using the intensity distribution of objects and backgrounds as prior information can simplify the process of establishing and solving the model. The idea of constructing our energy function is as follows. During the contour curve convergence, while maximizing distribution difference between the inside and outside of the active contour, the distribution difference between the inside/outside of contour and the prior object/background is minimized. We present experimental results on a variety of synthetic and natural images. Experimental results demonstrate the potential of the proposed method that with the information of prior distribution, the segmentation effect and speed can be both improved efficaciously.

Efficient optic disc (OD) segmentation plays a significant role in retinal image analysis and retinal disease screening. In this paper, we present a full-automatic segmentation approach called double boundary extraction for the OD segmentation. The proposed approach consists of the following two stages: first, we utilize an unsupervised learning technology and statistical method based on OD boundary information to obtain the initial contour adaptively. Second, the final optic disc boundary is extracted using the proposed LSO model. The performance of the proposed method is tested on the public DIARETDB1 database and the experimental results demonstrate the effectiveness and advantage of the proposed method.

In this paper, we propose a fully automatic method for extracting carotid artery contours from ultrasound images based on an active contour approach. Several contour extraction techniques have been proposed to measure carotid artery walls for early detection of atherosclerotic disease. However, the majority of these techniques require a certain degree of user interaction that demands time and effort. Our proposal automatically detects the position of the carotid artery by identifying blood flow information related to the carotid artery, and an active contour model is employed that uses initial contours placed in the detected position. Our method also applies a global energy minimization scheme to the active contour model. Experiments on clinical cases show that the proposed method automatically extracts the carotid artery contours at an accuracy close to that achieved by manual extraction.

Vector field convolution (VFC) provides a successful external force for an active contour model. However, it fails to extract the complex geometries, especially the deep concavity when the initial contour is set outside the object or the concave region. In this letter, dynamically constrained vector field convolution (DCVFC) external force is proposed to solve this problem. In DCVFC, the indicator function with respect to the evolving contour is introduced to restrain the correlation of external forces generated by different edges, and the forces dynamically generated by complex concave edges gradually make the contour move to the object. On the other hand, traditional vector field, a component of the proposed DCVFC, makes the evolving contour stop at the object boundary. The connections between VFC and DCVFC are also analyzed. DCVFC maintains desirable properties of VFC, such as robustness to initialization. Experimental results demonstrate that DCVFC snake provides a much better segmentation than VFC snake.

This paper combines the LBP operator and the active contour model. It introduces a salient gradient vector flow snake (SGVF snake), based on a novel edge map generated from the salient boundary point image (SBP image). The MDGVM criterion process helps to reduce feature detail and background noise as well as retaining the salient boundary points. The resultant SBP image as an edge map gives powerful support to the SGVF snake because of the inherent combination of the intensity, gradient and texture cues. Experiments prove that the MDGVM process has high efficiency in reducing outliers and the SGVF snake is a large improvement over the GVF snake for contour detection, especially in natural images with low contrast and small texture background.

Bone Mineral Density (BMD) is an indicator of osteoporosis that is an increasingly serious disease, particularly for the elderly. To calculate BMD, we need to measure the volume of the femur in a noninvasive way. In this paper, we propose a noninvasive bone volume measurement method using x-ray attenuation on radiography and medical knowledge. The absolute thickness at one reference pixel and the relative thickness at all pixels of the bone in the x-ray image are used to calculate the volume and the BMD. First, the absolute bone thickness of one particular pixel is estimated by the known geometric shape of a specific bone part as medical knowledge. The relative bone thicknesses of all pixels are then calculated by x-ray attenuation of each pixel. Finally, given the absolute bone thickness of the reference pixel, the absolute bone thickness of all pixels is mapped. To evaluate the performance of the proposed method, experiments on 300 subjects were performed. We found that the method provides good estimations of real BMD values of femur bone. Estimates shows a high linear correlation of 0.96 between the volume Bone Mineral Density (vBMD) of CT-SCAN and computed vBMD (all P<0.001). The BMD results reveal 3.23% difference in volume from the BMD of CT-SCAN.

Intelligent scissors is an interactive image segmentation algorithm which allows a user to select piece-wise globally optimal contour segment corresponding to a desired object boundary. However, the intelligent scissors is too sensitive to a noise and texture patterns in an image since it utilizes the gradient information concerning the pixel intensities. This paper describes a new intelligent scissors based on the concept of the separability in order to improve the object boundary extraction performance. The effectiveness of the proposed method has been confirmed by some experiments for actual images acquired by an ordinary digital camera.

This paper presents a motion-based boundary tracking method for a moving deformable object in an image sequence using a parametric active contour model. Deciding the local converging directions of the contour points is essential for correctly extracting the boundary of a moving deformable object. Thus, a new energy function for a parametric active contour model is proposed based on the addition of a directional energy term using a frame difference map to the greedy snake. The frame difference map is used to obtain motion information on an object with fast and non-rigid motion. Plus, updating rules for the frame difference map are also developed to encourage the stable convergence of the contour points. Experiments on a set of synthetic and real image sequences show that the proposed method could fully track a speedy deformable object while exactly extracting the boundary of the object in every frame.

To detect lung area, this paper proposes curve stopping function that is based on CT coefficient of area of lung parenchyma instead of existing edge indication function. The proposed method was compared numerically using various measures and this method can detect better lung parenchyma region than existing methods. In addition, detecting procedure of the area of lung parenchyma was visually verified in lung images.

Image segmentation is an essential technique of image analysis. In spite of the issues in contour initialization and boundary concavities, active contour models (snakes) are popular and successful methods for segmentation. In this paper, we present a new active contour model, Gaussian Gradient Force snake (GGF snake), for segmentation of an endoscopic image. The GGF snake is less sensitive to contour initialization and it ensures a high accuracy, large capture range, and fast CPU time for computing an external force. It was observed that the GGF snake produced more reasonable results in various image types : simple synthetic images, commercial digital camera images, and endoscopic images, than previous snakes did.

This paper describes a new method for detection and tracking of moving objects from a moving camera image sequence using robust estimation and active contour models. We assume that the apparent background motion between two consecutive image frames can be approximated by affine transformation. In order to register the static background, we estimate affine transformation parameters using LMedS (Least Median of Squares) method which is a kind of robust estimator. Split-and-merge contour models are employed for tracking multiple moving objects. Image energy of contour models is defined based on the image which is obtained by subtracting the previous frame transformed with estimated affine parameters from the current frame. We have implemented the method on an image processing system which consists of DSP boards for real-time tracking of moving objects from a moving camera image sequence.

In this paper a new snake model for image morphing with semiautomated delineation which depends on Hermite's interpolation theory, is presented. The snake model will be used to specify the correspondence between features in two given images. It allows a user to extract a contour that defines a facial feature such as the lips, mouth, and profile, by only specifying the endpoints of the contour around the feature which we wish to define. We assume that the user can specify the endpoints of a curve around the features that serve as the extremities of a contour. The proposed method automatically computes the image information around these endpoints which provides the boundary conditions. Then the contour is optimized by taking this information into account near its extremities. During the iterative optimization process, the image forces are turned on progressively from the contour extremities toward the center to define the exact position of the feature. The proposed algorithm helps the user to easily define the exact position of a feature. It may also reduce the time required to establish the features of an image.

This paper describes a new feature extraction model (Active Model) which is extended from the active contour model (Snakes). Active Model can be applied to various energy minimizing models since it integrates most of the energy terms ever proposed into one model and also provides the new terms for multiple images such as motion and stereo images. The computational order of energy minimization process is estimated in comparison with a dynamic programming method and a greedy algorithm, and it is shown that the energy minimization process in Active Model is faster than the others. Some experimental results are also shown.