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Jerdvisanop CHAKAROTHAI Katsumi FUJII Yukihisa SUZUKI Jun SHIBAYAMA Kanako WAKE
In this study, we develop a numerical method for determining transient energy deposition in biological bodies exposed to electromagnetic (EM) pulses. We use a newly developed frequency-dependent finite-difference time-domain (FD2TD) method, which is combined with the fast inverse Laplace transform (FILT) and Prony method. The FILT and Prony method are utilized to transform the Cole-Cole model of biological media into a sum of multiple Debye relaxation terms. Parameters of Debye terms are then extracted by comparison with the time-domain impulse responses. The extracted parameters are used in an FDTD formulation, which is derived using the auxiliary differential equation method, and transient energy deposition into a biological medium is calculated by the equivalent circuit method. The validity of our proposed method is demonstrated by comparing numerical results and those derived from an analytical method. Finally, transient energy deposition into human heads of TARO and HANAKO models is then calculated using the proposed method and, physical insights into pulse exposures of the human heads are provided.
Hiroki KAWAI Kanako WAKE Takuji ARIMA Soichi WATANABE
This paper proposes a head-local-exposure system using a figure-8 loop antenna for 2-GHz band operation. This system allows us to observe biological effects through microcirculation of the rat brain simultaneously with exposure through a cranial window, i.e., the window made by transparent glass and implanted on the surface of the rat brain. The specific absorption rate (SAR) in a rat exposed to microwaves due to the new exposure system is estimated numerically and experimentally. The ratio of averaged SAR between the target area, which is the brain's surface just under the cranial window, and the whole body is about 59 for the 8-week rat model and 13 for the 2-week rat model. This antenna achieves local exposure for the rat brain for 2-GHz band operation.
Jingjing SHI Jerdvisanop CHAKAROTHAI Jianqing WANG Kanako WAKE Soichi WATANABE Osamu FUJIWARA
With the rapid increase of various uses of wireless communications in modern life, the high microwave and millimeter wave frequency bands are attracting much attention. However, the existing databases on above 6GHz radio-frequency (RF) electromagnetic (EM) field exposure of biological bodies are obviously insufficient. An in-vivo research project on local and whole-body exposure of rats to RF-EM fields above 6GHz was started in Japan in 2013. This study aims to perform a dosimetric design for the whole-body-average specific absorption rates (WBA-SARs) of unconstrained rats exposed to 6GHz RF-EM fields in a reverberation chamber (RC). The required input power into the RC is clarified using a two-step evaluation method in order to achieve a target exposure level in rats. The two-step method, which incorporates the finite-difference time-domain (FDTD) numerical solutions with electric field measurements in an RC exposure system, is used as an evaluation method to determine the whole-body exposure level in the rats. In order to verify the validity of the two-step method, we use S-parameter measurements inside the RC to experimentally derive the WBA-SARs with rat-equivalent phantoms and then compare those with the FDTD-calculated ones. It was shown that the difference between the two-step method and the S-parameter measurements is within 1.63dB, which reveals the validity and usefulness of the two-step technique.
Jingjing SHI Jerdvisanop CHAKAROTHAI Jianqing WANG Kanako WAKE Soichi WATANABE Osamu FUJIWARA
This paper aims to achieve a high-quality exposure level quantification of whole-body average-specific absorption rates (WBA-SARs) for small animals in a medium-size reverberation chamber (RC). A two-step method, which incorporates the finite-difference time-domain (FDTD) numerical solutions with electric field measurements in an RC-type exposure system, has been used as an evaluation method to determine the whole-body exposure level in small animals. However, there is little data that quantitatively demonstrate the validity and accuracy of this method in an RC up to now. In order to clarify the validity of the two-step method, we compare the physical quantities in terms of electric field strength and WBA-SARs by using a direct numerical assessment method known as the method of moments (MoM) with ten homogenous gel phantoms placed in an RC with 2GHz exposure. The comparison results show that the relative errors between the two-step method and the MoM approach are approximately below 10%, which reveals the validity and usefulness of the two-step technique. Finally, we perform a dosimetric analysis of the WBA-SARs for anatomical mouse models with the two-step method and determine the input power related to our developed RC-exposure system to achieve a target exposure level in small animals.
Chiaki TAKASAKA Kazuyuki SAITO Masaharu TAKAHASHI Tomoaki NAGAOKA Kanako WAKE
Various electromagnetic (EM) wave applications have become commonplace, and humans are frequently exposed to EM waves. Therefore, the effect of EM waves on the human body should be evaluated. In this study, we focused on the specific absorption rate (SAR) due to the EM waves emitted from smartphones, developed high-resolution numerical smartphone models, and studied the SAR variation by changing the position and tilt angle (the angle between the display of the smartphone model and horizontal plane) of the smartphone models vis-à-vis the human abdomen, assuming the use of the smartphone at various tilt angles in front of the abdomen. The calculations showed that the surface shape of the human model influenced the SAR variation.
Nadege VARSIER Kanako WAKE Masao TAKI Soichi WATANABE
We compared SAR distributions in major anatomical structures of the brain of a homogeneous and a heterogeneous model using FDTD calculations. Our results proved a good correlation between SAR values in lobes of the brain where tumors may arise more frequently. However SAR values at some specific locations were shown to be under or overestimated.
Tomohide SONODA Rui TOKUNAGA Koichi SETO Yukihisa SUZUKI Kanako WAKE Soichi WATANABE Masao TAKI
In this paper, dosimetry of an in vitro exposure apparatus based on a cylindrical waveguide is performed. The SAR distributions are first obtained numerically by using FDTD method. The thermal fields in the medium are then estimated by numerical calculations of the equation of heat conduction. The maximum temperature rise for 17.9 W/kg average SAR during 3000 s exposure is about 2 on the bottom of the medium where cells are located. The thermal distribution is relatively uniform near the center of the dish and the temperature in this region is around 38.7. The results of the numerical calculation are experimentally supported. The results provide the electromagnetic and thermal characteristics of the exposure apparatus, which will define the exposure conditions of the planned experiments using this apparatus.