Recent studies in protein structure prediction such as AlphaFold have enabled deep learning to achieve great attention on the Drug-Target Affinity (DTA) task. Most works are dedicated to embed single molecular property and homogeneous information, ignoring the diverse heterogeneous information gains that are contained in the molecules and interactions. Motivated by this, we propose an end-to-end deep learning framework to perform Molecular Heterogeneous features Fusion (MolHF) for DTA prediction on heterogeneity. To address the challenges that biochemical attributes locates in different heterogeneous spaces, we design a Molecular Heterogeneous Information Learning module with multi-strategy learning. Especially, Molecular Heterogeneous Attention Fusion module is present to obtain the gains of molecular heterogeneous features. With these, the diversity of molecular structure information for drugs can be extracted. Extensive experiments on two benchmark datasets show that our method outperforms the baselines in all four metrics. Ablation studies validate the effect of attentive fusion and multi-group of drug heterogeneous features. Visual presentations demonstrate the impact of protein embedding level and the model ability of fitting data. In summary, the diverse gains brought by heterogeneous information contribute to drug-target affinity prediction.

Cross-modal hashing technology has attracted much attention for its favorable retrieval performance and low storage cost. However, for existing cross-modal hashing methods, the heterogeneity of data across modalities is still a challenge and how to fully explore and utilize the intra-modality features has not been well studied. In this paper, we propose a novel cross-modal hashing approach called Modality-fused Graph Network (MFGN). The network architecture consists of a text channel and an image channel that are used to learn modality-specific features, and a modality fusion channel that uses the graph network to learn the modality-shared representations to reduce the heterogeneity across modalities. In addition, an integration module is introduced for the image and text channels to fully explore intra-modality features. Experiments on two widely used datasets show that our approach achieves better results than the state-of-the-art cross-modal hashing methods.

Sketch face recognition is to match sketch face images to photo face images. The main challenge of sketch face recognition is learning discriminative feature representations to ensure intra-class compactness and inter-class separability. However, traditional sketch face recognition methods encouraged samples with the same identity to get closer, and samples with different identities to be further, and these methods did not consider the intra-class compactness of samples. In this paper, we propose triplet-margin-center loss to cope with the above problem by combining the triplet loss and center loss. The triplet-margin-center loss can enlarge the distance of inter-class samples and reduce intra-class sample variations simultaneously, and improve intra-class compactness. Moreover, the triplet-margin-center loss applies a hard triplet sample selection strategy. It aims to effectively select hard samples to avoid unstable training phase and slow converges. With our approach, the samples from photos and from sketches taken from the same identity are closer, and samples from photos and sketches come from different identities are further in the projected space. In extensive experiments and comparisons with the state-of-the-art methods, our approach achieves marked improvements in most cases.

Detecting anomalies, such as network failure or intentional attack in Internet, is a vital but challenging task. Although numerous techniques have been developed based on Internet traffic, detecting anomalies from the perspective of Internet topology structure is going to be possible because the anomaly detection of structured datasets based on complex network theory has become a focus of attention recently. In this paper, an anomaly detection method for the large-scale Internet topology is proposed to detect local structure crashes caused by the cascading failure. In order to quantify the dynamic changes of Internet topology, the network path changes coefficient (NPCC) is put forward which highlights the Internet abnormal state after it is attacked continuously. Furthermore, inspired by Fibonacci Sequence, we proposed the decision function that can determine whether the Internet is abnormal or not. That is the current Internet is abnormal if its NPCC is out of the normal domain calculated using the previous k NPCCs of Internet topology. Finally the new Internet anomaly detection method is tested against the topology data of three Internet anomaly events. The results show that the detection accuracy of all events are over 97%, the detection precision for three events are 90.24%, 83.33% and 66.67%, when k=36. According to the experimental values of index F1, larger values of k offer better detection performance. Meanwhile, our method has better performance for the anomaly behaviors caused by network failure than those caused by intentional attack. Compared with traditional anomaly detection methods, our work is more simple and powerful for the government or organization in items of detecting large-scale abnormal events.

Currently, the most advanced knowledge distillation models use a metric learning approach based on probability distributions. However, the correlation between supervised probability distributions is typically geometric and implicit, causing inefficiency and an inability to capture structural feature representations among different tasks. To overcome this problem, we propose a knowledge distillation loss using the robust sliced Wasserstein distance with geometric median (GMSW) to estimate the differences between the teacher and student representations. Due to the intuitive geometric properties of GMSW, the student model can effectively learn to align its produced hidden states from the teacher model, thereby establishing a robust correlation among implicit features. In experiment, our method outperforms state-of-the-art models in both high-resource and low-resource settings.

In the past few years, discriminant analysis and manifold learning have been widely used in feature extraction. Recently, the sparse representation technique has advanced the development of pattern recognition. In this paper, we combine both discriminant analysis and manifold learning with sparse representation technique and propose a novel feature extraction approach named sparsity preserving embedding with manifold learning and discriminant analysis. It seeks an embedded space, where not only the sparse reconstructive relations among original samples are preserved, but also the manifold and discriminant information of both original sample set and the corresponding reconstructed sample set is maintained. Experimental results on the public AR and FERET face databases show that our approach outperforms relevant methods in recognition performance.

In Digital Library (DL) applications, digital book clustering is an important and urgent research task. However, it is difficult to conduct effectively because of the great length of digital books. To do the correct clustering for digital books, a novel method based on probabilistic topic model is proposed. Firstly, we build a topic model named LDAC. The main goal of LDAC topic modeling is to effectively extract topics from digital books. Subsequently, Gibbs sampling is applied for parameter inference. Once the model parameters are learned, each book is assigned to the cluster which maximizes the posterior probability. Experimental results demonstrate that our approach based on LDAC is able to achieve significant improvement as compared to the related methods.

Cross-project defect prediction (CPDP) is a research hot recently, which utilizes the data form existing source project to construct prediction model and predicts the defect-prone of software instances from target project. However, it is challenging in bridging the distribution difference between different projects. To minimize the data distribution differences between different projects and predict unlabeled target instances, we present a novel approach called selective pseudo-labeling based subspace learning (SPSL). SPSL learns a common subspace by using both labeled source instances and pseudo-labeled target instances. The accuracy of pseudo-labeling is promoted by iterative selective pseudo-labeling strategy. The pseudo-labeled instances from target project are iteratively updated by selecting the instances with high confidence from two pseudo-labeling technologies. Experiments are conducted on AEEEM dataset and the results show that SPSL is effective for CPDP.

This letter addresses the problem of space-time adaptive processing (STAP) for airborne nonuniform linear array (NLA) radar using a generalized sidelobe canceller (GSC). Due to the difficulty of determining the spatial nulls for the NLAs, it is a problem to obtain a valid blocking matrix (BM) of the GSC directly. In order to solve this problem and improve the STAP performance, a BM modification method based on the modified Gram-Schmidt orthogonalization algorithm is proposed. The modified GSC processor can achieve the optimal STAP performance and as well a faster convergence rate than the orthogonal subspace projection method. Numerical simulations validate the effectiveness of the proposed methods.

Cross-project defect prediction (CPDP) is a hot research topic in recent years. The inconsistent data distribution between source and target projects and lack of labels for most of target instances bring a challenge for defect prediction. Researchers have developed several CPDP methods. However, the prediction performance still needs to be improved. In this paper, we propose a novel approach called Joint Domain Adaption and Pseudo-Labeling (JDAPL). The network architecture consists of a feature mapping sub-network to map source and target instances into a common subspace, followed by a classification sub-network and an auxiliary classification sub-network. The classification sub-network makes use of the label information of labeled instances to generate pseudo-labels. The auxiliary classification sub-network learns to reduce the distribution difference and improve the accuracy of pseudo-labels for unlabeled instances through loss maximization. Network training is guided by the adversarial scheme. Extensive experiments are conducted on 10 projects of the AEEEM and NASA datasets, and the results indicate that our approach achieves better performance compared with the baselines.

Cross-project defect prediction (CPDP) is a feasible solution to build an accurate prediction model without enough historical data. Although existing methods for CPDP that use only labeled data to build the prediction model achieve great results, there are much room left to further improve on prediction performance. In this paper we propose a Semi-Supervised Discriminative Feature Learning (SSDFL) approach for CPDP. SSDFL first transfers knowledge of source and target data into the common space by using a fully-connected neural network to mine potential similarities of source and target data. Next, we reduce the differences of both marginal distributions and conditional distributions between mapped source and target data. We also introduce the discriminative feature learning to make full use of label information, which is that the instances from the same class are close to each other and the instances from different classes are distant from each other. Extensive experiments are conducted on 10 projects from AEEEM and NASA datasets, and the experimental results indicate that our approach obtains better prediction performance than baselines.

In this letter, a statistical uncorrelated near class discriminant (SUNCD) approach is proposed for face recognition. The optimal discriminant vector obtained by this approach can differentiate one class and its near classes, i.e., its nearest neighbor classes, by constructing the specific between-class and within-class scatter matrices and using the Fisher criterion. In this manner, SUNCD acquires all discriminant vectors class by class. Furthermore, SUNCD makes every discriminant vector satisfy locally statistical uncorrelated constraints by using the corresponding class and part of its most neighboring classes. Experiments on the public AR face database demonstrate that the proposed approach outperforms several representative discriminant methods.

Recently, multi-view dictionary learning technique has attracted lots of research interest. Although several multi-view dictionary learning methods have been addressed, they can be further improved. Most of existing multi-view dictionary learning methods adopt the l0 or l1-norm sparsity constraint on the representation coefficients, which makes the training and testing phases time-consuming. In this paper, we propose a novel multi-view dictionary learning approach named multi-view synthesis and analysis dictionaries learning (MSADL), which jointly learns multiple discriminant dictionary pairs with each corresponding to one view and containing a structured synthesis dictionary and a structured analysis dictionary. MSADL utilizes synthesis dictionaries to achieve class-specific reconstruction and uses analysis dictionaries to generate discriminative code coefficients by linear projection. Furthermore, we design an uncorrelation term for multi-view dictionary learning, such that the redundancy among synthesis dictionaries learned from different views can be reduced. Two widely used datasets are employed as test data. Experimental results demonstrate the efficiency and effectiveness of the proposed approach.

This letter proposes a nonlinear DCT discriminant feature extraction approach for face recognition. The proposed approach first selects appropriate DCT frequency bands according to their levels of nonlinear discrimination. Then, this approach extracts nonlinear discriminant features from the selected DCT bands by presenting a new kernel discriminant method, i.e. the improved kernel discriminative common vector (KDCV) method. Experiments on the public FERET database show that this new approach is more effective than several related methods.

In a heterogeneous unreliable multiaccess network, wherein terminals share a common wireless channel with distinct error probabilities, existing works have shown that a persistent round-robin (RR-P) scheduling policy can be arbitrarily worse than the optimum in terms of Age of Information (AoI) under standard Automatic Repeat reQuest (ARQ). In this paper, practical Hybrid ARQ (HARQ) schemes which are widely-used in today's wireless networks are considered. We show that RR-P is very close to optimum with asymptotically many terminals in this case, by explicitly deriving tight, closed-form AoI gaps between optimum and achievable AoI by RR-P. In particular, it is rigorously proved that for RR-P, under HARQ models concerning fading channels (resp. finite-blocklength regime), the relative AoI gap compared with the optimum is within a constant of 6.4% (resp. 6.2% with error exponential decay rate of 0.5). In addition, RR-P enjoys the distinctive advantage of implementation simplicity with channel-unaware and easy-to-decentralize operations, making it favorable in practice. A further investigation considering constraint imposed on the number of retransmissions is presented. The performance gap is indicated through numerical simulations.

Hardware implementation of neural networks usually have high computational complexity that increase exponentially with the size of a circuit, leading to more uncertain and unreliable circuit performance. This letter presents a novel Radial Basis Function (RBF) neural network based on parallel fault tolerant stochastic computing, in which number is converted from deterministic domain to probabilistic domain. The Gaussian RBF for middle layer neuron is implemented using stochastic structure that reduce the hardware resources significantly. Our experimental results from two pattern recognition tests (the Thomas gestures and the MIT faces) show that the stochastic design is capable to maintain equivalent performance when the stream length set to 10Kbits. The stochastic hidden neuron uses only 1.2% hardware resource compared with the CORDIC algorithm. Furthermore, the proposed algorithm is very flexible in design tradeoff between computing accuracy, power consumption and chip area.