Person authentication using biometric information has recently become popular among researchers. User management based on biometrics is more reliable than that using conventional methods. To secure private information, it is necessary to build continuous authentication-based user management systems. Brain waves are suitable biometric modalities for continuous authentication. This study is based on biometric authentication using brain waves evoked by invisible visual stimuli. Invisible visual stimulation is considered over visual stimulation to overcome the obstacles faced by a user when using a system. Invisible stimuli are confirmed by changing the intensity of the image and presenting high-speed stimulation. To ensure invisibility, stimuli of different intensities were tested, and the stimuli with an intensity of 5% was confirmed to be invisible. To improve the verification performance, a continuous wavelet transform was introduced over the Fourier transform because it extracts both time and frequency information from the brain wave. The scalogram obtained by the wavelet transform was used as an individual feature and for synchronizing the template and test data. Furthermore, to improve the synchronization performance, the waveband was split based on the power distribution of the scalogram. A performance evaluation using 20 subjects showed an equal error rate of 3.8%.

Electrophysiology, which is the study of the electrical properties of biological tissues and cells, has become indispensable in modern clinical research, diagnostics, disease monitoring and therapeutics. In this paper we present a brief history of this discipline and how integrated circuit design shaped electrophysiology in the last few decades. We will discuss how biopotential amplifier design has evolved from the classical three-opamp architecture to more advanced high-performance circuits enabling long-term wearable monitoring of the autonomous and central nervous system. We will also discuss how these integrated circuits evolved to measure in-vivo neural circuits. This paper targets readers who are new to the domain of biopotential recording and want to get a brief historical overview and get up to speed on the main circuit design concepts for both wearable and in-vivo biopotential recording.

We characterized prion disease by comparing brain functional connectivity network (BFCN), which were constructed by 16-ch scalp-recorded electroencephalograms (EEGs). The connectivity between each pair of nodes (electrodes) were computed by synchronization likelihood (SL). The BFCN was applied to graph theory to discriminate prion disease patients from healthy elderlies and dementia groups.

We propose a sampling method that incorporates a normally distributed sampling series for EEG measurements using compressed sensing. We confirmed that the ADC sampling count and amount of wirelessly transmitted data can be reduced by 11% while maintaining a reconstruction accuracy similar to that of the conventional method.

Music is often used for emotion induction because it can change the emotions of people. However, since we subjectively feel different emotions when listening to music, we propose an emotion induction system that generates music that is adapted to each individual. Our system automatically generates suitable music for emotion induction based on the emotions predicted from an electroencephalogram (EEG). We examined three elements for constructing our system: 1) a music generator that creates music that induces emotions that resemble the inputs, 2) emotion prediction using EEG in real-time, and 3) the control of a music generator using the predicted emotions for making music that is suitable for inducing emotions. We constructed our proposed system using these elements and evaluated it. The results showed its effectiveness for inducing emotions and suggest that feedback loops that tailor stimuli to individuals can successfully induce emotions.

This letter reports on the effectiveness of applying the K-singular value decomposition (SVD) dictionary learning to the electroencephalogram (EEG) compressed sensing framework with outlier detection and independent component analysis. Using the K-SVD dictionary matrix with our design parameter optimization, for example, at compression ratio of four, we improved the normalized mean square error value by 31.4% compared with that of the discrete cosine transform dictionary for CHB-MIT Scalp EEG Database.

This paper proposes a novel compressed sensing (CS) framework for reconstructing electroencephalogram (EEG) signals. A feature of this framework is the application of independent component analysis (ICA) to remove the interference from artifacts after undersampling in a data processing unit. Therefore, we can remove the ICA processing block from the sensing unit. In this framework, we used a random undersampling measurement matrix to suppress the Gaussian. The developed framework, in which the discrete cosine transform basis and orthogonal matching pursuit were used, was evaluated using raw EEG signals with a pseudo-model of an eye-blink artifact. The normalized mean square error (NMSE) and correlation coefficient (CC), obtained as the average of 2,000 results, were compared to quantitatively demonstrate the effectiveness of the proposed framework. The evaluation results of the NMSE and CC showed that the proposed framework could remove the interference from the artifacts under a high compression ratio.

Hum noise such as power line interference is one of the critical problems in the biomedical signal acquisition. Various techniques have been proposed to suppress power line interference. However, some of the techniques require more components and power consumption. The notch depth in the conventional N-path notch filter circuits needs a higher number of paths and switches off-resistance. It makes the conventional N-path notch filter less of efficiency to suppress hum noise. This work proposed the new N-path notch filter to hum noise suppression in biomedical signal acquisition. The new N-path notch filter achieved notch depth above 40dB with sampling frequency 50Hz and 60Hz. Although the proposed circuits use less number of path and switches off-resistance. The proposed circuit has been verified using artificial ECG signal contaminated by hum noise at frequency 50Hz and 60Hz. The output of N-path notch filter achieved a noise-free signal even if the sampling frequency changes.

The brain processes numerous information related to traffic scenes for appropriate perception, judgment, and operation in vehicle driving. Here, the strategy for perception, judgment, and operation is individually different for each driver, and this difference is thought to be arise from experience of driving. In the present work, we measure and analyze human brain activity (EEG: Electroencephalogram) related to visual perception during vehicle driving to clarify the relationship between experience of driving and brain activity. As a result, more experts generate α activities than beginners, and also confirm that the β activities is reduced than beginners. These results firstly indicate that experience of driving is reflected into the activation pattern of EEG.

Biometric authentication, namely using biometric features for authentication is gaining popularity in recent years as further modalities, such as fingerprint, iris, face, voice, gait, and others are exploited. We explore the effectiveness of three simple Electroencephalography (EEG) related biometric authentication tasks, namely resting, thinking about a picture, and moving a single finger. We present details of the data processing steps we exploit for authentication, including extracting features from the frequency power spectrum and MFCC, and training a multilayer perceptron classifier for authentication. For evaluation purposes, we record an EEG dataset of 27 test subjects. We use three setups, baseline, task-agnostic, and task-specific, to investigate whether person-specific features can be detected across different tasks for authentication. We further evaluate, whether different tasks can be distinguished. Our results suggest that tasks are distinguishable, as well as that our authentication approach can work both exploiting features from a specific, fixed, task as well as using features across different tasks.

Most recent work used raw electroencephalograph (EEG) data to train deep learning (DL) models, with the assumption that DL models can learn discriminative features by itself. It is not yet clear what kind of RSVP specific features can be selected and combined with EEG raw data to improve the RSVP classification performance of DL models. In this paper, we tried to extract RSVP specific features and combined them with EEG raw data to capture more spatial and temporal correlations of target or non-target event and improve the EEG-based RSVP target detection performance. We tested on X2 Expertise RSVP dataset to show the experiment results. We conducted detailed performance evaluations among different features and feature combinations with traditional classification models and different CNN models for within-subject and cross-subject test. Compared with state-of-the-art traditional Bagging Tree (BT) and Bayesian Linear Discriminant Analysis (BLDA) classifiers, our proposed combined features with CNN models achieved 1.1% better performance in within-subject test and 2% better performance in cross-subject test. This shed light on the ability for the combined features to be an efficient tool in RSVP target detection with deep learning models and thus improved the performance of RSVP target detection.

Brain-computer interfaces (BCIs) have been used by users to convey their intentions directly with brain signals. For example, a spelling system that uses EEGs allows letters on a display to be selected. In comparison, previous studies have investigated decoding speech information such as syllables, words from single-trial brain signals during speech comprehension, or articulatory imagination. Such decoding realizes speech recognition with a relatively short time-lag and without relying on a display. Previous magnetoencephalogram (MEG) research showed that a template matching method could be used to classify three English sentences by using phase patterns in theta oscillations. This method is based on the synchronization between speech rhythms and neural oscillations during speech processing, that is, theta oscillations synchronized with syllabic rhythms and low-gamma oscillations with phonemic rhythms. The present study aimed to approximate this classification method to a BCI application. To this end, (1) we investigated the performance of the EEG-based classification of three Japanese sentences and (2) evaluated the generalizability of our models to other different users. For the purpose of improving accuracy, (3) we investigated the performances of four classifiers: template matching (baseline), logistic regression, support vector machine, and random forest. In addition, (4) we propose using novel features including phase patterns in a higher frequency range. Our proposed features were constructed in order to capture synchronization in a low-gamma band, that is, (i) phases in EEG oscillations in the range of 2-50 Hz from all electrodes used for measuring EEG data (all) and (ii) phases selected on the basis of feature importance (selected). The classification results showed that, except for random forest, most classifiers perform similarly. Our proposed features improved the classification accuracy with statistical significance compared with a baseline feature, which is a phase pattern in neural oscillations in the range of 4-8 Hz from the right hemisphere. The best mean accuracy across folds was 55.9% using template matching trained by all features. We concluded that the use of phase information in a higher frequency band improves the performance of EEG-based sentence classification and that this model is applicable to other different users.

This paper describes the background noise estimation technique of the tensor product expansion with absolute error (TPE-AE) to estimate multiple sources. The electroencephalogram (EEG) signal produced by the saccadic eye movement is adopted to analyze relationship between a brain function and a human activity. The electrooculogram (EOG) generated by eye movements yields significant problems for the EEG analysis. The denoising of EOG artifacts is important task to perform an accurate analysis. In this paper, the two types of TPE-AE are proposed to estimates EOG and other components in EEG during eye movement. One technique estimates two outer products using median filter based TPE-AE. The another technique uses a reference signal to separate the two sources. We show that the proposed method is effective to estimate and separate two sources in EEG.

Power line noise is one of critical problems in bio-sensing. Various approaches utilizing both analog and digital techniques has been proposed. However, these approaches need active circuits with a wide dynamic range. N-path notch filters which implementable using passive components can be a promising solution to this problem. However, the notch depth of a conventional N-path notch filter is limited by the number of path. A new N-path notch filter with additional S/H circuit is proposed. Simulation results show that the proposed topology improves the notch depth by 43dB.

In this paper a new method for noise removal from single-trial event-related potentials recorded with a multi-channel electroencephalogram is addressed. An observed signal is separated into multiple signals with a multi-channel Wiener filter whose coefficients are estimated based on parameter estimation of a probabilistic generative model that locally models the amplitude of each separated signal in the time-frequency domain. Effectiveness of using prior information about covariance matrices to estimate model parameters and frequency dependent covariance matrices were shown through an experiment with a simulated event-related potential data set.

We have proposed a new Bayesian network model (BNM) framework for single-trial-EEG-based Brain-Computer Interface (BCI). The BNM was constructed in the following. In order to discriminate between left and right hands to be imaged from single-trial EEGs measured during the movement imagery tasks, the BNM has the following three steps: (1) independent component analysis (ICA) for each of the single-trial EEGs; (2) equivalent current dipole source localization (ECDL) for projections of each IC on the scalp surface; (3) BNM construction using the ECDL results. The BNMs were composed of nodes and edges which correspond to the brain sites where ECDs are located, and their connections, respectively. The connections were quantified as node activities by conditional probabilities calculated by probabilistic inference in each trial. The BNM-based BCI is compared with the common spatial pattern (CSP) method. For ten healthy subjects, there was no significant difference between the two methods. Our BNM might reflect each subject's strategy for task execution.

This letter presents a new entropy measure for electroencephalograms (EEGs), which reflects the underlying dynamics of EEG over multiple time scales. The motivation behind this study is that neurological signals such as EEG possess distinct dynamics over different spectral modes. To deal with the nonlinear and nonstationary nature of EEG, the recently developed empirical mode decomposition (EMD) is incorporated, allowing an EEG to be decomposed into its inherent spectral components, referred to as intrinsic mode functions (IMFs). By calculating Shannon entropy of IMFs in a time-dependent manner and summing them over adaptive multiple scales, the result is an adaptive subscale entropy measure of EEG. Simulation and experimental results show that the proposed entropy properly reveals the dynamical changes over multiple scales.

In this paper, we propose a novel incremental method for discovering latent variables from multivariate data with high efficiency. It integrates non-Gaussianity and an adaptive incremental model in an unsupervised way to extract informative features. Our proposed method discovers a small number of compact features from a very large number of features and can still achieve good predictive performance in EEG signals. The promising EEG signal classification results from our experiments prove that this approach can successfully extract important features. Our proposed method also has low memory requirements and computational costs.

We developed a novel movement-imagery-based brain-computer interface (BCI) for untrained subjects without employing machine learning techniques. The development of BCI consisted of several steps. First, spline Laplacian analysis was performed. Next, time-frequency analysis was applied to determine the optimal frequency range and latencies of the electroencephalograms (EEGs). Finally, trials were classified as right or left based on β-band event-related synchronization using the cumulative distribution function of pretrigger EEG noise. To test the performance of the BCI, EEGs during the execution and imagination of right/left wrist-bending movements were measured from 63 locations over the entire scalp using eight healthy subjects. The highest classification accuracies were 84.4% and 77.8% for real movements and their imageries, respectively. The accuracy is significantly higher than that of previously reported machine-learning-based BCIs in the movement imagery task (paired t-test, p < 0.05). It has also been demonstrated that the highest accuracy was achieved even though subjects had never participated in movement imageries.

The present study examined the evaluation of aging using the photic driving response, a measure used in routine EEG examinations. We examined 60 normal participants without EEG abnormalities, classified into three age groups (2029, 3059 and over 60 years; 20 participants per group). EEG was measured at rest and during photic stimulation (PS). We calculated Z-scores as a measure of enhancement and suppression due to visual stimulation at rest and during PS and tested for between-group and intraindividual differences. We examined responses in the alpha frequency and harmonic frequency ranges separately, because alpha suppression can affect harmonic frequency responses that overlap the alpha frequency band. We found a negative correlation between Z-scores for harmonics and age by fitting the data to a linear function (CC: -0.740). In contrast, Z-scores and alpha frequency were positively correlated (CC: 0.590).