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101-120hit(16348hit)

  • Dual-Path Convolutional Neural Network Based on Band Interaction Block for Acoustic Scene Classification Open Access

    Pengxu JIANG  Yang YANG  Yue XIE  Cairong ZOU  Qingyun WANG  

     
    LETTER-Engineering Acoustics

      Pubricized:
    2023/10/04
      Vol:
    E107-A No:7
      Page(s):
    1040-1044

    Convolutional neural network (CNN) is widely used in acoustic scene classification (ASC) tasks. In most cases, local convolution is utilized to gather time-frequency information between spectrum nodes. It is challenging to adequately express the non-local link between frequency domains in a finite convolution region. In this paper, we propose a dual-path convolutional neural network based on band interaction block (DCNN-bi) for ASC, with mel-spectrogram as the model’s input. We build two parallel CNN paths to learn the high-frequency and low-frequency components of the input feature. Additionally, we have created three band interaction blocks (bi-blocks) to explore the pertinent nodes between various frequency bands, which are connected between two paths. Combining the time-frequency information from two paths, the bi-blocks with three distinct designs acquire non-local information and send it back to the respective paths. The experimental results indicate that the utilization of the bi-block has the potential to improve the initial performance of the CNN substantially. Specifically, when applied to the DCASE 2018 and DCASE 2020 datasets, the CNN exhibited performance improvements of 1.79% and 3.06%, respectively.

  • A Frequency Estimation Algorithm for High Precision Monitoring of Significant Space Targets Open Access

    Ze Fu GAO  Wen Ge YANG  Yi Wen JIAO  

     
    LETTER-Communication Theory and Signals

      Pubricized:
    2023/09/26
      Vol:
    E107-A No:7
      Page(s):
    1058-1061

    Space is becoming increasingly congested and contested, which calls for effective means to conduct effective monitoring of high-value space assets, especially in Space Situational Awareness (SSA) missions, while there are imperfections in existing methods and corresponding algorithms. To overcome such a problem, this letter proposes an algorithm for accurate Connected Element Interferometry (CEI) in SSA based on more interpolation information and iterations. Simulation results show that: (i) after iterations, the estimated asymptotic variance of the proposed method can basically achieve uniform convergence, and the ratio of it to ACRB is 1.00235 in δ0 ∈ [-0.5, 0.5], which is closer to 1 than the current best AM algorithms; (ii) In the interval of SNR ∈ [-14dB, 0dB], the estimation error of the proposed algorithm decreases significantly, which is basically comparable to CRLB (maintains at 1.236 times). The research of this letter could play a significant role in effective monitoring and high-precision tracking and measurement with significant space targets during futuristic SSA missions.

  • A High-Performance Antenna Array Signal Processing Method in Deep Space Communication Open Access

    Yi Wen JIAO  Ze Fu GAO  Wen Ge YANG  

     
    LETTER-Communication Theory and Signals

      Pubricized:
    2023/09/25
      Vol:
    E107-A No:7
      Page(s):
    1062-1065

    In future deep space communication missions, VLBI (Very Long Baseline Interferometry) based on antenna array technology remains a critical detection method, which urgently requires the improvement of synthesis performance for antenna array signals. Considering this, focusing on optimizing the traditional antenna grouping method applied in the phase estimation algorithm, this letter proposes a “L/2 to L/2” antenna grouping method based on the maximum correlation signal-to-noise ratio (SNR). Following this idea, a phase difference estimation algorithm named “Couple” is presented. Theoretical analysis and simulation verification illustrate that: when ρ < -10dB, the proposed “Couple” has the highest performance; increasing the number of antennas can significantly improve its synthetic loss performance and robustness. The research of this letter indicates a promising potential in supporting the rising deep space exploration and communication missions.

  • A Retinal Vessel Segmentation Network Fusing Cross-Modal Features Open Access

    Xiaosheng YU  Jianning CHI  Ming XU  

     
    LETTER-Image

      Pubricized:
    2023/11/01
      Vol:
    E107-A No:7
      Page(s):
    1071-1075

    Accurate segmentation of fundus vessel structure can effectively assist doctors in diagnosing eye diseases. In this paper, we propose a fundus blood vessel segmentation network combined with cross-modal features and verify our method on the public data set OCTA-500. Experimental results show that our method has high accuracy and robustness.

  • Dither Signal Design for PAPR Reduction in OFDM-IM over a Rayleigh Fading Channel Open Access

    Kee-Hoon KIM  

     
    PAPER-Wireless Communication Technologies

      Vol:
    E107-B No:7
      Page(s):
    505-512

    Orthogonal frequency division multiplexing with index modulation (OFDM-IM) is a novel scheme where the information bits are conveyed through the subcarrier activation pattern (SAP) and the symbols on the active subcarriers. Specifically, the subcarriers are partitioned into many subblocks and the subcarriers in each subblock can have two states, active or idle. Unfortunately, OFDM-IM inherits the high peak-to-average power ratio (PAPR) problem from the classical OFDM. The OFDM-IM signal with high PAPR induces in-band distortion and out-of-band radiation when it passes through high power amplifier (HPA). Recently, there are attempts to reduce PAPR by exploiting the unique structure of OFDM-IM, which is adding dither signals in the idle subcarriers. The most recent work dealing with the dither signals is using dithers signals with various amplitude constraints according to the characteristic of the corresponding OFDM-IM subblock. This is reasonable because OFDM subblocks have distinct levels of robustness against noise. However, the amplitude constraint in the recent work is efficient for only additive white Gaussian noise (AWGN) channels and cannot be used for maximum likelihood (ML) detection. Therefore, in this paper, based on pairwise error probability (PEP) analysis, a specific constraint for the dither signals is derived over a Rayleigh fading channel.

  • Determination Method of Cascaded Number for Lumped Parameter Models Oriented to Transmission Lines Open Access

    Risheng QIN  Hua KUANG  He JIANG  Hui YU  Hong LI  Zhuan LI  

     
    PAPER-Electronic Circuits

      Pubricized:
    2023/12/20
      Vol:
    E107-C No:7
      Page(s):
    201-209

    This paper proposes a determination method of the cascaded number for lumped parameter models (LPMs) of the transmission lines. The LPM is used to simulate long-distance transmission lines, and the cascaded number significantly impacts the simulation results. Currently, there is a lack of a system-level determination method of the cascaded number for LPMs. Based on the theoretical analysis and eigenvalue decomposition of network matrix, this paper discusses the error in resonance characteristics between distributed parameter model and LPMs. Moreover, it is deduced that optimal cascaded numbers of the cascaded π-type and T-type LPMs are the same, and the Γ-type LPM has a lowest analog accuracy. The principle that the maximum simulation frequency is less than the first resonance frequency of each segment is presented. According to the principle, optimal cascaded numbers of cascaded π-type, T-type, and Γ-type LPMs are obtained. The effectiveness of the proposed determination method is verified by simulation.

  • Power Peak Load Forecasting Based on Deep Time Series Analysis Method Open Access

    Ying-Chang HUNG  Duen-Ren LIU  

     
    PAPER-Artificial Intelligence, Data Mining

      Pubricized:
    2024/03/21
      Vol:
    E107-D No:7
      Page(s):
    845-856

    The prediction of peak power load is a critical factor directly impacting the stability of power supply, characterized significantly by its time series nature and intricate ties to the seasonal patterns in electricity usage. Despite its crucial importance, the current landscape of power peak load forecasting remains a multifaceted challenge in the field. This study aims to contribute to this domain by proposing a method that leverages a combination of three primary models - the GRU model, self-attention mechanism, and Transformer mechanism - to forecast peak power load. To contextualize this research within the ongoing discourse, it’s essential to consider the evolving methodologies and advancements in power peak load forecasting. By delving into additional references addressing the complexities and current state of the power peak load forecasting problem, this study aims to build upon the existing knowledge base and offer insights into contemporary challenges and strategies adopted within the field. Data preprocessing in this study involves comprehensive cleaning, standardization, and the design of relevant functions to ensure robustness in the predictive modeling process. Additionally, recognizing the necessity to capture temporal changes effectively, this research incorporates features such as “Weekly Moving Average” and “Monthly Moving Average” into the dataset. To evaluate the proposed methodologies comprehensively, this study conducts comparative analyses with established models such as LSTM, Self-attention network, Transformer, ARIMA, and SVR. The outcomes reveal that the models proposed in this study exhibit superior predictive performance compared to these established models, showcasing their effectiveness in accurately forecasting electricity consumption. The significance of this research lies in two primary contributions. Firstly, it introduces an innovative prediction method combining the GRU model, self-attention mechanism, and Transformer mechanism, aligning with the contemporary evolution of predictive modeling techniques in the field. Secondly, it introduces and emphasizes the utility of “Weekly Moving Average” and “Monthly Moving Average” methodologies, crucial in effectively capturing and interpreting seasonal variations within the dataset. By incorporating these features, this study enhances the model’s ability to account for seasonal influencing factors, thereby significantly improving the accuracy of peak power load forecasting. This contribution aligns with the ongoing efforts to refine forecasting methodologies and addresses the pertinent challenges within power peak load forecasting.

  • Conflict Management Method Based on a New Belief Divergence in Evidence Theory Open Access

    Zhu YIN  Xiaojian MA  Hang WANG  

     
    PAPER-Office Information Systems, e-Business Modeling

      Pubricized:
    2024/03/01
      Vol:
    E107-D No:7
      Page(s):
    857-868

    Highly conflicting evidence that may lead to the counter-intuitive results is one of the challenges for information fusion in Dempster-Shafer evidence theory. To deal with this issue, evidence conflict is investigated based on belief divergence measuring the discrepancy between evidence. In this paper, the pignistic probability transform belief χ2 divergence, named as BBχ2 divergence, is proposed. By introducing the pignistic probability transform, the proposed BBχ2 divergence can accurately quantify the difference between evidence with the consideration of multi-element sets. Compared with a few belief divergences, the novel divergence has more precision. Based on this advantageous divergence, a new multi-source information fusion method is devised. The proposed method considers both credibility weights and information volume weights to determine the overall weight of each evidence. Eventually, the proposed method is applied in target recognition and fault diagnosis, in which comparative analysis indicates that the proposed method can realize the highest accuracy for managing evidence conflict.

  • Operational Resilience of Network Considering Common-Cause Failures Open Access

    Tetsushi YUGE  Yasumasa SAGAWA  Natsumi TAKAHASHI  

     
    PAPER-Reliability, Maintainability and Safety Analysis

      Pubricized:
    2023/09/11
      Vol:
    E107-A No:6
      Page(s):
    855-863

    This paper discusses the resilience of networks based on graph theory and stochastic process. The electric power network where edges may fail simultaneously and the performance of the network is measured by the ratio of connected nodes is supposed for the target network. For the restoration, under the constraint that the resources are limited, the failed edges are repaired one by one, and the order of the repair for several failed edges is determined with the priority to the edge that the amount of increasing system performance is the largest after the completion of repair. Two types of resilience are discussed, one is resilience in the recovery stage according to the conventional definition of resilience and the other is steady state operational resilience considering the long-term operation in which the network state changes stochastically. The second represents a comprehensive capacity of resilience for a system and is analytically derived by Markov analysis. We assume that the large-scale disruption occurs due to the simultaneous failure of edges caused by the common cause failures in the analysis. Marshall-Olkin type shock model and α factor method are incorporated to model the common cause failures. Then two resilience measures, “operational resilience” and “operational resilience in recovery stage” are proposed. We also propose approximation methods to obtain these two operational resilience measures for complex networks.

  • Analysis of Blood Cell Image Recognition Methods Based on Improved CNN and Vision Transformer Open Access

    Pingping WANG  Xinyi ZHANG  Yuyan ZHAO  Yueti LI  Kaisheng XU  Shuaiyin ZHAO  

     
    PAPER-Neural Networks and Bioengineering

      Pubricized:
    2023/09/15
      Vol:
    E107-A No:6
      Page(s):
    899-908

    Leukemia is a common and highly dangerous blood disease that requires early detection and treatment. Currently, the diagnosis of leukemia types mainly relies on the pathologist’s morphological examination of blood cell images, which is a tedious and time-consuming process, and the diagnosis results are highly subjective and prone to misdiagnosis and missed diagnosis. This research suggests a blood cell image recognition technique based on an enhanced Vision Transformer to address these problems. Firstly, this paper incorporate convolutions with token embedding to replace the positional encoding which represent coarse spatial information. Then based on the Transformer’s self-attention mechanism, this paper proposes a sparse attention module that can select identifying regions in the image, further enhancing the model’s fine-grained feature expression capability. Finally, this paper uses a contrastive loss function to further increase the intra-class consistency and inter-class difference of classification features. According to experimental results, The model in this study has an identification accuracy of 92.49% on the Munich single-cell morphological dataset, which is an improvement of 1.41% over the baseline. And comparing with sota Swin transformer, this method still get greater performance. So our method has the potential to provide reference for clinical diagnosis by physicians.

  • Dynamic Limited Variable Step-Size Algorithm Based on the MSD Variation Cost Function Open Access

    Yufei HAN  Jiaye XIE  Yibo LI  

     
    LETTER-Digital Signal Processing

      Pubricized:
    2023/09/11
      Vol:
    E107-A No:6
      Page(s):
    919-922

    The steady-state and convergence performances are important indicators to evaluate adaptive algorithms. The step-size affects these two important indicators directly. Many relevant scholars have also proposed some variable step-size adaptive algorithms for improving performance. However, there are still some problems in these existing variable step-size adaptive algorithms, such as the insufficient theoretical analysis, the imbalanced performance and the unachievable parameter. These problems influence the actual performance of some algorithms greatly. Therefore, we intend to further explore an inherent relationship between the key performance and the step-size in this paper. The variation of mean square deviation (MSD) is adopted as the cost function. Based on some theoretical analyses and derivations, a novel variable step-size algorithm with a dynamic limited function (DLF) was proposed. At the same time, the sufficient theoretical analysis is conducted on the weight deviation and the convergence stability. The proposed algorithm is also tested with some typical algorithms in many different environments. Both the theoretical analysis and the experimental result all have verified that the proposed algorithm equips a superior performance.

  • Secrecy Outage Probability and Secrecy Diversity Order of Alamouti STBC with Decision Feedback Detection over Time-Selective Fading Channels Open Access

    Gyulim KIM  Hoojin LEE  Xinrong LI  Seong Ho CHAE  

     
    LETTER-Communication Theory and Signals

      Pubricized:
    2023/09/19
      Vol:
    E107-A No:6
      Page(s):
    923-927

    This letter studies the secrecy outage probability (SOP) and the secrecy diversity order of Alamouti STBC with decision feedback (DF) detection over the time-selective fading channels. For given temporal correlations, we have derived the exact SOPs and their asymptotic approximations for all possible combinations of detection schemes including joint maximum likehood (JML), zero-forcing (ZF), and DF at Bob and Eve. We reveal that the SOP is mainly influenced by the detection scheme of the legitimate receiver rather than eavesdropper and the achievable secrecy diversity order converges to two and one for JML only at Bob (i.e., JML-JML/ZF/DF) and for the other cases (i.e., ZF-JML/ZF/DF, DF-JML/ZF/DF), respectively. Here, p-q combination pair indicates that Bob and Eve adopt the detection method p ∈ {JML, ZF, DF} and q ∈ {JML, ZF, DF}, respectively.

  • An Adaptively Biased OFDM Based on Hartley Transform for Visible Light Communication Systems Open Access

    Menglong WU  Yongfa XIE  Yongchao SHI  Jianwen ZHANG  Tianao YAO  Wenkai LIU  

     
    LETTER-Communication Theory and Signals

      Pubricized:
    2023/09/20
      Vol:
    E107-A No:6
      Page(s):
    928-931

    Direct-current biased optical orthogonal frequency division multiplexing (DCO-OFDM) converts bipolar OFDM signals into unipolar non-negative signals by introducing a high DC bias, which satisfies the requirement that the signal transmitted by intensity modulated/direct detection (IM/DD) must be positive. However, the high DC bias results in low power efficiency of DCO-OFDM. An adaptively biased optical OFDM was proposed, which could be designed with different biases according to the signal amplitude to improve power efficiency in this letter. The adaptive bias does not need to be taken off deliberately at the receiver, and the interference caused by the adaptive bias will only be placed on the reserved subcarriers, which will not affect the effective information. Moreover, the proposed OFDM uses Hartley transform instead of Fourier transform used in conventional optical OFDM, which makes this OFDM have low computational complexity and high spectral efficiency. The simulation results show that the normalized optical bit energy to noise power ratio (Eb(opt)/N0) required by the proposed OFDM at the bit error rate (BER) of 10-3 is, on average, 7.5 dB and 3.4 dB lower than that of DCO-OFDM and superimposed asymmetrically clipped optical OFDM (ACO-OFDM), respectively.

  • Physical Layer Security Enhancement for mmWave System with Multiple RISs and Imperfect CSI Open Access

    Qingqing TU  Zheng DONG  Xianbing ZOU  Ning WEI  

     
    PAPER-Fundamental Theories for Communications

      Vol:
    E107-B No:6
      Page(s):
    430-445

    Despite the appealing advantages of reconfigurable intelligent surfaces (RIS) aided mmWave communications, there remain practical issues that need to be addressed before the large-scale deployment of RISs in future wireless networks. In this study, we jointly consider the non-neglectable practical issues in a multi-RIS-aided mmWave system, which can significantly affect the secrecy performance, including the high computational complexity, imperfect channel state information (CSI), and finite resolution of phase shifters. To solve this non-convex challenging stochastic optimization problem, we propose a robust and low-complexity algorithm to maximize the achievable secrete rate. Specially, by combining the benefits of fractional programming and the stochastic successive convex approximation techniques, we transform the joint optimization problem into some convex ones and solve them sub-optimally. The theoretical analysis and simulation results demonstrate that the proposed algorithms could mitigate the joint negative effects of practical issues and yielded a tradeoff between secure performance and complexity/overhead outperforming non-robust benchmarks, which increases the robustness and flexibility of multiple RIS deployments in future wireless networks.

  • Federated Deep Reinforcement Learning for Multimedia Task Offloading and Resource Allocation in MEC Networks Open Access

    Rongqi ZHANG  Chunyun PAN  Yafei WANG  Yuanyuan YAO  Xuehua LI  

     
    PAPER-Network

      Vol:
    E107-B No:6
      Page(s):
    446-457

    With maturation of 5G technology in recent years, multimedia services such as live video streaming and online games on the Internet have flourished. These multimedia services frequently require low latency, which pose a significant challenge to compute the high latency requirements multimedia tasks. Mobile edge computing (MEC), is considered a key technology solution to address the above challenges. It offloads computation-intensive tasks to edge servers by sinking mobile nodes, which reduces task execution latency and relieves computing pressure on multimedia devices. In order to use MEC paradigm reasonably and efficiently, resource allocation has become a new challenge. In this paper, we focus on the multimedia tasks which need to be uploaded and processed in the network. We set the optimization problem with the goal of minimizing the latency and energy consumption required to perform tasks in multimedia devices. To solve the complex and non-convex problem, we formulate the optimization problem as a distributed deep reinforcement learning (DRL) problem and propose a federated Dueling deep Q-network (DDQN) based multimedia task offloading and resource allocation algorithm (FDRL-DDQN). In the algorithm, DRL is trained on the local device, while federated learning (FL) is responsible for aggregating and updating the parameters from the trained local models. Further, in order to solve the not identically and independently distributed (non-IID) data problem of multimedia devices, we develop a method for selecting participating federated devices. The simulation results show that the FDRL-DDQN algorithm can reduce the total cost by 31.3% compared to the DQN algorithm when the task data is 1000 kbit, and the maximum reduction can be 35.3% compared to the traditional baseline algorithm.

  • A Novel Remote-Tracking Heart Rate Measurement Method Based on Stepping Motor and mm-Wave FMCW Radar Open Access

    Yaokun HU  Xuanyu PENG  Takeshi TODA  

     
    PAPER-Sensing

      Vol:
    E107-B No:6
      Page(s):
    470-486

    The subject must be motionless for conventional radar-based non-contact vital signs measurements. Additionally, the measurement range is limited by the design of the radar module itself. Although the accuracy of measurements has been improving, the prospects for their application could have been faster to develop. This paper proposed a novel radar-based adaptive tracking method for measuring the heart rate of the moving monitored person. The radar module is fixed on a circular plate and driven by stepping motors to rotate it. In order to protect the user’s privacy, the method uses radar signal processing to detect the subject’s position to control a stepping motor that adjusts the radar’s measurement range. The results of the fixed-route experiments revealed that when the subject was moving at a speed of 0.5 m/s, the mean values of RMSE for heart rate measurements were all below 2.85 beat per minute (bpm), and when moving at a speed of 1 m/s, they were all below 4.05 bpm. When subjects walked at random routes and speeds, the RMSE of the measurements were all below 6.85 bpm, with a mean value of 4.35 bpm. The average RR interval time of the reconstructed heartbeat signal was highly correlated with the electrocardiography (ECG) data, with a correlation coefficient of 0.9905. In addition, this study not only evaluated the potential effect of arm swing (more normal walking motion) on heart rate measurement but also demonstrated the ability of the proposed method to measure heart rate in a multiple-people scenario.

  • A 0.13 mJ/Prediction CIFAR-100 Fully Synthesizable Raster-Scan-Based Wired-Logic Processor in 16-nm FPGA Open Access

    Dongzhu LI  Zhijie ZHAN  Rei SUMIKAWA  Mototsugu HAMADA  Atsutake KOSUGE  Tadahiro KURODA  

     
    PAPER

      Pubricized:
    2023/11/24
      Vol:
    E107-C No:6
      Page(s):
    155-162

    A 0.13mJ/prediction with 68.6% accuracy wired-logic deep neural network (DNN) processor is developed in a single 16-nm field-programmable gate array (FPGA) chip. Compared with conventional von-Neumann architecture DNN processors, the energy efficiency is greatly improved by eliminating DRAM/BRAM access. A technical challenge for conventional wired-logic processors is the large amount of hardware resources required for implementing large-scale neural networks. To implement a large-scale convolutional neural network (CNN) into a single FPGA chip, two technologies are introduced: (1) a sparse neural network known as a non-linear neural network (NNN), and (2) a newly developed raster-scan wired-logic architecture. Furthermore, a novel high-level synthesis (HLS) technique for wired-logic processor is proposed. The proposed HLS technique enables the automatic generation of two key components: (1) Verilog-hardware description language (HDL) code for a raster-scan-based wired-logic processor and (2) test bench code for conducting equivalence checking. The automated process significantly mitigates the time and effort required for implementation and debugging. Compared with the state-of-the-art FPGA-based processor, 238 times better energy efficiency is achieved with only a slight decrease in accuracy on the CIFAR-100 task. In addition, 7 times better energy efficiency is achieved compared with the state-of-the-art network-optimized application-specific integrated circuit (ASIC).

  • Development of Tunnel Magneto-Resistive Sensors Open Access

    Mikihiko OOGANE  

     
    INVITED PAPER

      Pubricized:
    2023/12/04
      Vol:
    E107-C No:6
      Page(s):
    171-175

    The magnetic field resolution of the tunnel magneto-resistive (TMR) sensors has been improving and it reaches below 1.0 pT/Hz0.5 at low frequency. The real-time measurement of the magnetocardiography (MCG) and the measurement of the magnetoencephalography (MEG) have been demonstrated by developed TMR sensors. Although the MCG and MEG have been applied to diagnosis of diseases, the conventional MCG/MEG system using superconducting quantum interference devices (SQUIDs) cannot measure the signal by touching the body, the body must be fixed, and maintenance costs are huge. The MCG/MEG system with TMR sensors operating at room temperature have the potential to solve these problems. In addition, it has the great advantage that it does not require a special magnetic shielded room. Further developments are expected to progress to maximize these unique features of TMR sensors.

  • Estimation of Core Size Distribution of Magnetic Nanoparticles Using High-Tc SQUID Magnetometer and Particle Swarm Optimizer-Based Inversion Technique Open Access

    Mohd Mawardi SAARI  Mohd Herwan SULAIMAN  Toshihiko KIWA  

     
    PAPER

      Pubricized:
    2023/10/25
      Vol:
    E107-C No:6
      Page(s):
    176-182

    In this work, the core size estimation technique of magnetic nanoparticles (MNPs) using the static magnetization curve obtained from a high-Tc SQUID magnetometer and a metaheuristic inversion technique based on the Particle Swarm Optimizer (PSO) algorithm is presented. The high-Tc SQUID magnetometer is constructed from a high-Tc SQUID sensor coupled by a flux transformer to sense the modulated magnetization signal from a sample. The magnetization signal is modulated by the lateral vibration of the sample on top of a planar differential detection coil of the flux transformer. A pair of primary and excitation coils are utilized to apply an excitation field parallel to the sensitive axis of the detection coil. Using the high-Tc SQUID magnetometer, the magnetization curve of a commercial MNP sample (Resovist) was measured in a logarithmic scale of the excitation field. The PSO inverse technique is then applied to the magnetization curve to construct the magnetic moment distribution. A multimodal normalized log-normal distribution was used in the minimization of the objective function of the PSO inversion technique, and a modification of the PSO search region is proposed to improve the exploration and exploitation of the PSO particles. As a result, a good agreement on the Resovist magnetic core size was obtained between the proposed technique and the non-negative least square (NNLS) inversion technique. The estimated core sizes of 8.0484 nm and 20.3018 nm agreed well with the values reported in the literature using the commercial low-Tc SQUID magnetometer with the SVD and NNLS inversion techniques. Compared to the NNLS inversion technique, the PSO inversion technique had merits in exploring an optimal core size distribution freely without being regularized by a parameter and facilitating an easy peak position determination owing to the smoothness of the constructed distribution. The combination of the high-Tc SQUID magnetometer and the PSO-based reconstruction technique offers a powerful approach for characterizing the MNP core size distribution, and further improvements can be expected from the recent state-of-the-art optimization algorithm to optimize further the computation time and the best objective function value.

  • Development of Liquid-Phase Bioassay Using AC Susceptibility Measurement of Magnetic Nanoparticles Open Access

    Takako MIZOGUCHI  Akihiko KANDORI  Keiji ENPUKU  

     
    PAPER

      Pubricized:
    2023/11/21
      Vol:
    E107-C No:6
      Page(s):
    183-189

    Simple and quick tests at medical clinics have become increasingly important. Magnetic sensing techniques have been developed to detect biomarkers using magnetic nanoparticles in liquid-phase assays. We developed a biomarker assay that involves using an alternating current (AC) susceptibility measurement system that uses functional magnetic particles and magnetic sensing technology. We also developed compact biomarker measuring equipment to enable quick testing. Our assay is a one-step homogeneous assay that involves simply mixing a sample with a reagent, shortening testing time and simplifying processing. Using our compact measuring equipment, which includes anisotropic magneto resistance (AMR) sensors, we conducted high-sensitivity measurements of extremely small amounts of two biomarkers (C-reactive protein, CRP and α-Fetoprotein, AFP) used for diagnosing arteriosclerosis and malignant tumors. The results indicate that an extremely small amount of CRP and AFP could be detected within 15 min, which demonstrated the possibility of a simple and quick high-sensitivity immunoassay that involves using an AC-susceptibility measurement system.

101-120hit(16348hit)